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The only shared downstream effect is increased energy expenditure, but even that occurs through completely different mechanisms: Retatrutide through glucagon-driven thermogenesis, and Tesamorelin through growth hormone-mediated metabolic activity

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Mean GSH levels increased consistently with time relative to baseline (Table 2 and Figure 3a,b), although levels fluctuated somewhat among individual subjects (Figure 3c,d)

As discussed in Section 5, the 90% clearance rate of liver fat makes Retatrutide a potential first-line therapy for those at risk of liver fibrosis or cirrhosis, even if their primary goal isn't just aesthetic weight loss